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KMID : 0388220140210060317
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Journal of the Korean Rheumatism Association
2014 Volume.21 No. 6 p.317 ~ p.321
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A Case of Dermatomyositis Complicated with Pneumomediastinum Successfully treated with Cyclosporine A: a Case Report and Review of Literature
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Chung Joo-Young
Yoon Ha-Yong
Choi Yun-Jung
Song Soo-Kyeong
Lee Won-Seok
Yoo Wan-Hee
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Abstract
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Dermatomyositis (DM) is a systemic inflammatory disease affecting skeletal muscles and other organs. Spontaneous pneumomediastinum (PnM) has been previously reported as a rare complication of DM and it is known to occur more frequently in patients with interstitial lung disease (ILD). Here we report on a case of a 52-year-old woman with DM who developed spontaneous PnM, which was treated successfully with high-dose steroid pulse therapy and cyclosporine A (CsA). This case suggests that CsA can be an effective therapeutic agent in DM refractory to glu-cocorticoid therapy, with ILD or pulmonary fibrosis ac-companied by DM. CsA should be considered as an initial immunosuppressive agent for patients with PnM in DM.
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KEYWORD
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Dermatomyositis, Pneumomediastinum, Inte-rstitial lung disease, Cyclosporin
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